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Isolated paraaortic lymph‐node recurrence after the curative resection of colorectal carcinoma
Author(s) -
Min Byung Soh,
Kim Nam Kyu,
Sohn Seung Kook,
Cho Chang Hwan,
Lee Kang Young,
Baik Seung Hyuk
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20926
Subject(s) - medicine , paraaortic lymph nodes , carcinoembryonic antigen , lymph node , colorectal cancer , carcinoma , surgery , chemotherapy , radiology , gastroenterology , cancer , metastasis
Background and objectives Isolated paraaortic lymph‐node recurrence (IPLR) after curative surgery for colorectal carcinoma is rare and no previous report has specifically addressed this type of recurrence. We investigated the clinical features of IPLR and analyzed prognostic factors. Methods Of 2,916 patients who underwent curative surgery for colorectal carcinoma, IPLR was identified in 38 patients (1.3%). The clinical features and prognostic factors of these patients were analyzed. Results IPLR was first detected by increased serum carcinoembryonic antigen (CEA) levels (63.2%) or by routine follow‐up computed tomography (CT) (36.8%). Curative resection of IPLR was performed in six patients (15.8%). A total of 19 patients (50.0%) received chemoradiation therapy and 13 patients (34.2%) received chemotherapy only. The median survival from IPLR was 13 months (range: 5–60 months). The median survival time from IPLR for the resected patients was 34 months, whereas it was 12 months for those who did not undergo resection ( P = 0.034). The factors associated with the prognosis were histological grade ( P = 0.003), location ( P = 0.032), and resection of IPLR ( P = 0.034). Conclusions IPLR after curative surgery for colorectal carcinoma is rare. Although it is generally associated with poor prognosis, better survival might be achieved through curative resection in selected cases. J. Surg. Oncol. 2008;97:136–140. © 2007 Wiley‐Liss, Inc.