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Impact of pre‐ and postoperative multimodality therapy on rectal cancer
Author(s) -
Boller AnneMarie,
Cima Robert R.
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20919
Subject(s) - medicine , multimodality , colorectal cancer , cancer , general surgery , surgery , philosophy , linguistics
Surgery is the primary treatment of rectal cancer. However, variability in surgical outcomes led to development of combined therapies including pelvic radiation and systemic chemotherapy. The evolution of these therapies both individually and combined, their successes and limitations is discussed in the context of an evolving understanding of rectal cancer biology. The impact of standardized optimal surgery on the need for additional therapy and trends in treating complete responders to neoadjuvant therapy is also reviewed. J. Surg. Oncol. 2007;96:665–670. © 2007 Wiley‐Liss, Inc.