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The biologic significance of micrometastatic disease and sentinel lymph node technology on colorectal cancer
Author(s) -
Iddings Douglas,
Bilchik Anton
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20918
Subject(s) - medicine , colorectal cancer , sentinel lymph node , oncology , sentinel node , disease , lymph node , cancer , lymph , pathology , breast cancer
The sentinel lymph node (SLN) technique has practical applications in multiple solid tumors including colorectal carcinoma. Identifying the SLN(s) provides better staging of the regional lymphatics beyond standard H&E analysis. This additional information assists in predicting biology and may be useful in guiding adjuvant therapy. We postulate the era of sentinel node has ushered in a new generation of node‐negative patients; patients that have an exceptionally favorable outcome when compared to historic controls. J. Surg. Oncol. 2007;96:671–677. © 2007 Wiley‐Liss, Inc.