The biologic significance of micrometastatic disease and sentinel lymph node technology on colorectal cancer | Zendy

Iddings Douglas | Zendy; Bilchik Anton | Zendy

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The biologic significance of micrometastatic disease and sentinel lymph node technology on colorectal cancer

Author(s) -

Iddings Douglas,

Bilchik Anton

Publication year - 2007

Publication title -

journal of surgical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.201

H-Index - 111

eISSN - 1096-9098

pISSN - 0022-4790

DOI - 10.1002/jso.20918

Subject(s) - medicine , colorectal cancer , sentinel lymph node , oncology , sentinel node , disease , lymph node , cancer , lymph , pathology , breast cancer

The sentinel lymph node (SLN) technique has practical applications in multiple solid tumors including colorectal carcinoma. Identifying the SLN(s) provides better staging of the regional lymphatics beyond standard H&E analysis. This additional information assists in predicting biology and may be useful in guiding adjuvant therapy. We postulate the era of sentinel node has ushered in a new generation of node‐negative patients; patients that have an exceptionally favorable outcome when compared to historic controls. J. Surg. Oncol. 2007;96:671–677. © 2007 Wiley‐Liss, Inc.

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