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Molecular profiling and risk stratification of adenocarcinoma of the colon
Author(s) -
Mutch Matthew G.
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20915
Subject(s) - medicine , risk stratification , colorectal cancer , adenocarcinoma , oncology , profiling (computer programming) , molecular biomarkers , cancer , computer science , operating system
Staging systems are used to predict the clinical and biologic behavior of tumors. This manuscript examines several molecular markers that hope to improve staging for colon cancer. It is unclear if a molecular marker, genetic signature, or a combination of histologic, genetic, and molecular parameters will provide the best prognostic information. What is clear is that more accurate staging tools are needed so patients receive the best therapy. J. Surg. Oncol. 2007;96:693–703. © 2007 Wiley‐Liss, Inc.