Radioimmunoguided surgery (RIGS), PET/CT image‐guided surgery, and fluorescence image‐guided surgery: Past, present, and future | Zendy

Sun Duxin | Zendy; Bloomston Mark | Zendy; Hinkle George | Zendy; AlSaif Osama Habib | Zendy; Hall Nathan C. | Zendy; Povoski Stephen P. | Zendy; Arnold Mark W. | Zendy; Martin Edward W. | Zendy

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Radioimmunoguided surgery (RIGS), PET/CT image‐guided surgery, and fluorescence image‐guided surgery: Past, present, and future

Author(s) -

Sun Duxin,

Bloomston Mark,

Hinkle George,

AlSaif Osama Habib,

Hall Nathan C.,

Povoski Stephen P.,

Arnold Mark W.,

Martin Edward W.

Publication year - 2007

Publication title -

journal of surgical oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.201

H-Index - 111

eISSN - 1096-9098

pISSN - 0022-4790

DOI - 10.1002/jso.20869

Subject(s) - medicine , occult , image guided surgery , radiology , nuclear medicine , pathology , alternative medicine

125 I‐labeled anti‐TAG‐72 antibodies were applied in radioimmunoguided surgery (RIGS) to remove gross and occult tumors. It is challenging to handle 125 I‐labeled materials. PET/CT image‐guided surgery utilizes 18 FDG to monitor the biochemical activity of the tumor and to integrate pre‐ and postoperative imaging for complete tumor removal. PET/CT image‐guided surgery only detects later stage disease. Fluorescence image‐guided surgery using anti‐TAG‐72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors. J. Surg. Oncol. 2007;96:297–308. © 2007 Wiley‐Liss, Inc.

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