Premium
Radioimmunoguided surgery (RIGS), PET/CT image‐guided surgery, and fluorescence image‐guided surgery: Past, present, and future
Author(s) -
Sun Duxin,
Bloomston Mark,
Hinkle George,
AlSaif Osama Habib,
Hall Nathan C.,
Povoski Stephen P.,
Arnold Mark W.,
Martin Edward W.
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20869
Subject(s) - medicine , occult , image guided surgery , radiology , nuclear medicine , pathology , alternative medicine
125 I‐labeled anti‐TAG‐72 antibodies were applied in radioimmunoguided surgery (RIGS) to remove gross and occult tumors. It is challenging to handle 125 I‐labeled materials. PET/CT image‐guided surgery utilizes 18 FDG to monitor the biochemical activity of the tumor and to integrate pre‐ and postoperative imaging for complete tumor removal. PET/CT image‐guided surgery only detects later stage disease. Fluorescence image‐guided surgery using anti‐TAG‐72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors. J. Surg. Oncol. 2007;96:297–308. © 2007 Wiley‐Liss, Inc.