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Benign glandular inclusions a rare cause of a false positive sentinel node
Author(s) -
Norton Laura E.,
Komenaka Ian K.,
Emerson Robert E.,
Murphy Colleen,
Badve Sunil
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20749
Subject(s) - medicine , sentinel node , biopsy , atypia , lumpectomy , pathology , sentinel lymph node , lymph node , adenocarcinoma , pathological , mastectomy , cancer , breast cancer
An 84‐year‐old female underwent a wire‐guided lumpectomy and sentinel lymph node biopsy. Two sentinel nodes were identified and sent for immediate pathological evaluation. One of the nodes was reported as “glandular epithelium consistent with metastatic adenocarcinoma.” Permanent sections of the sentinel node initially considered positive revealed glandular structures primarily within the fibrous capsule of the involved lymph node. These glands were lined by tall columnar epithelial cells, which had cilia on the luminal surface and did not show significant cytologic atypia. The limitations of intra‐operative evaluation of sentinel nodes make differentiation of uncommon pathology difficult. A conservative approach should be taken with these lesions as permanent sections will often elucidate the diagnosis. J. Surg. Oncol. 2007;95:593–596. © 2007 Wiley‐Liss, Inc.