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Is hepatic transplantation justified for primary liver cancer?
Author(s) -
Fisher Robert A.,
Maluf Daniel G.,
Wolfe Luke,
Williams Bridgette,
Cotterell Adrian,
Stravitz R. Todd,
Heuman Douglas,
Posner Marc
Publication year - 2007
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20617
Subject(s) - medicine , liver transplantation , hepatocellular carcinoma , population , liver cancer , transplantation , cancer , milan criteria , surgery , randomized controlled trial , oncology , environmental health
A concise, yet objective overview of Hepatocellular Carcinoma (HCC) treatment in 2006 with an intent to transplant is presented. The most significant variables impacting on the use of hepatic transplantation as therapy for primary liver cancer are developed under the headings of: Staging Criteria; Organ allocation; Transplant dropout minimization therapies; and Effects on the HCC general population. The pertinent medical literature and update of an ongoing intent‐to‐treat HCC with transplant single center randomized control trial are reviewed. J. Surg. Oncol. 2007;95:674–679. © 2007 Wiley‐Liss, Inc.