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Management of goblet cell carcinoid
Author(s) -
Byrn John C.,
Wang JuLin,
Divino Celia M.,
Nguyen Scott Q.,
Warner Richard R.P.
Publication year - 2006
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20587
Subject(s) - medicine , abdominal mass , appendix , presentation (obstetrics) , laparotomy , appendicitis , goblet cell , carcinoid tumors , gastroenterology , exacerbation , general surgery , surgery , pathology , paleontology , biology , epithelium
Background and Objectives Goblet cell carcinoid, a rare tumor of intermediate malignant potential, is known to account for a significant minority of appendiceal neoplasms. Sixteen new cases of gastrointestinal goblet cell carcinoid were reviewed to describe their presentation, treatment, and outcome. Methods A review of 16 cases from a single institution. Results Sixteen patients were diagnosed with goblet cell carcinoid between 1995 and 2005. Presenting diagnoses included appendicitis (n = 8), abdominal or liver mass (n = 5), uterine fibroids (n = 1), ovarian mass (n = 1), and Crohn's Disease exacerbation (n = 1). Mean follow‐up was 12 months with a mortality of 19% (n = 3). Patients were divided into two groups: those where the diagnosis was an incidental finding at operation (Group 1) and those where the presentation was of an abdominal mass or metastatic disease (Group 2). Nine of ten patients in Group 1 initially received appendectomies. Group 2 included patients presenting with Krukenberg type lesions (n = 2) and abdominal masses (n = 4). Conclusions Goblet cell carcinoid is a rare malignant tumor largely affecting the appendix. In patients presenting with appendicitis, our series does not support the recommendation of right hemicolectomy based on pathologic diagnosis alone and surgical intervention must be customized to the individual patient. J. Surg. Oncol. 2006;94:396–402. © 2006 Wiley‐Liss, Inc.