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The efficacy of breast MRI in predicting breast conservation therapy
Author(s) -
Blair Sarah,
Mcelroy Michele,
Middleton Michael S.,
Comstock Chris,
Wolfson Tanya,
Kamrava Mitch,
Wallace Anne,
Mortimer Joanne
Publication year - 2006
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20561
Subject(s) - medicine , breast mri , breast cancer , mastectomy , radiology , prospective cohort study , magnetic resonance imaging , mammography , cancer , surgery
Abstract Background Breast conservation therapy (BCT) has equal efficacy compared to mastectomy in treating breast cancer. Accurate pre‐operative measurement of tumor size can limit re‐excision procedures. Breast MRI may improve pre‐operative evaluation of extent of disease. Objective To examine the correlation of extent of disease on breast MRI with pathologic data to determine the utility of breast MRI in surgical planning of BCT. Methods We retrospectively reviewed our prospective database of women undergoing breast MRI. We identified 115 women with breast cancer who underwent a breast MRI and a surgical resection from 2000 to 2003. We compared patients with high‐grade tumors (HG, n = 40) to patients with low grade (LG, n = 75). Results The size of the tumor on MRI correlated with the pathologic size for HG tumors (HG R = 0.76 vs. LG R = 0.45, P = 0.033). Mastectomy was performed in 53 patients. In 10 patients with LG tumors, the MRI findings overestimated their disease. In 11 out of 115 patients the primary tumor or a second tumor was only seen by MRI. Conclusion Breast MRI does change surgical management by detecting additional malignancies. Breast MRI is accurate in staging extent of disease in the breast in patients with HG tumors. J. Surg. Oncol. 2006;94:220–225. © 2006 Wiley‐Liss, Inc.