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An objective assessment of demography of gallbladder cancer
Author(s) -
Kumar J. Ram,
Tewari Mallika,
Rai Arundhati,
Sinha Rohan,
Mohapatra Sadhu C.,
Shukla Hari S.
Publication year - 2006
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20526
Subject(s) - medicine , gallbladder cancer , socioeconomic status , demography , disease , odds ratio , population , gallbladder disease , epidemiology , ethnic group , family history , cancer , gallbladder , environmental health , sociology , anthropology
Background and Objectives Gallbladder cancer (GBC) is a lethal disease with a wide geographical, ethnic, and cultural variation suggesting major environmental influences such as diet and life style factors in the development of disease. An objective assessment of demographic profile and full implication of these features to recognize the population at risk is needed. This study was therefore undertaken to study the demography of GBC in Varanasi. Methods A retrospective study as a case—control model comprised 328 cases of GBC and 328 controls with gallstone disease (GSD). The relevant demographic data were collected and analyzed for identification of independent significant features and for the risk of GBC based on these features by calculating odds ratio. Results and Conclusions GBC predominantly a disease of females belonged to fourth and fifth decade of life. Among 328 cases of GBC only 75 were male and 253 female (M:F = 1:3.37). Majority of GBC patients were above 40 years and multiparous females. Family history of GBC was higher in GBC patients. Majority of GBC patients were of low socioeconomic status and hailed from rural background. This group tends to consume open mustard oil and water from hand pump. This study emphasizes the usefulness of demographic evaluation in diagnosis of GBC and a systematic approach to assessment of demographic features of GBC is recommended. J. Surg. Oncol. 2006;93:610–614. © 2006 Wiley‐Liss, Inc.