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cDNA microarray‐based translational research in soft tissue sarcoma
Author(s) -
Lubieniecka Joanna M.,
Nielsen Torsten O.
Publication year - 2005
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20409
Subject(s) - synovial sarcoma , medicine , sarcoma , translational research , soft tissue sarcoma , complementary dna , tissue microarray , microarray , soft tissue , pathology , computational biology , gene chip analysis , bioinformatics , cancer research , immunohistochemistry , biology , gene expression , gene , genetics
The authors discuss application of cDNA microarray technology in translational research to identify diagnostic markers and therapeutic targets in adult soft tissue sarcoma. Recent results in synovial sarcoma are used to highlight the applicability of this technology for marker and target discovery, as well as the need for preclinical validation of putative therapeutic targets. J. Surg. Oncol. 2005;92:267–271. © 2005 Wiley‐Liss, Inc.