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Calcium phosphate cement in musculoskeletal tumor surgery
Author(s) -
Matsumine Akihiko,
Kusuzaki Katsuyuki,
Matsubara Takao,
Okamura Atsushi,
Okuyama Noritaka,
Miyazaki Shinichi,
Shintani Ken,
Uchida Atsumasa
Publication year - 2006
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20355
Subject(s) - medicine , surgery , curettage , orthopedic surgery , bone cement , radiography , thrombosis , deep vein , radiodensity , cement , archaeology , history
Abstract Background and Objectives Calcium phosphate cement (CPC) is an injectable biocompatible bone substitute that has been used for various applications in orthopedic surgery. However, no extensive clinical studies of the use of CPC to fill bone cavities after curettage of musculoskeletal tumors have been reported. The present study reviewed the results for 56 musculoskeletal tumors treated by curettage and CPC implantation. Methods Assessment was based on clinical examination and radiographic findings. Variables for clinical assessment included pain, limb function, and complications. Median follow‐up was 18.5 months (range 6–47 months). Results One patient experienced post‐operative fractures. Three patients displayed local recurrence. One patient developed post‐operative superficial wound infection, and two patients with large bony defect exhibited non‐infectious serous discharge. No serious adverse effects such as deep venous thrombosis, pulmonary embolism were encountered. In all cases, CPC was radiographically well adapted to the surrounding host bone as of final follow‐up. Conclusions CPC appears to offer a useful bone substitute for the treatment of musculoskeletal tumors. As the follow‐up period for this study was short, further long‐term follow‐up studies are needed. J. Surg. Oncol. 2006;93: 212–220. © 2006 Wiley‐Liss, Inc.