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Role of dynamic sentinel node biopsy in penile cancer: Our experience
Author(s) -
Perdonà S.,
Autorino R.,
Gallo L.,
Di Lorenzo G.,
Cascini G.L.,
Lastoria F.,
Marra L.,
De Sio M.,
Damiano R.,
Gallo A.
Publication year - 2006
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20308
Subject(s) - medicine , sentinel node , penile cancer , biopsy , cancer , general surgery , surgery , radiology , breast cancer
Background and Objectives We report our initial experience with a relatively new technique, the so‐called “dynamic sentinel node biopsy”, in patients with penile cancer. Methods From January 2001 to February 2003, 17 consecutive patients with bilateral, clinically node negative penile cancer were enrolled. Dynamic sentinel node biopsy was followed by local excision of the primary lesion or penile amputation during the same session. Standard inguinal node dissection was performed 4 weeks after the first operation in all the patients. Results Pre‐operative lymphoscintigraphy revealed no sentinel nodes in 1, unilateral sentinel nodes in 5, and bilateral in 11 patients. Metastases were noted in 5 out of 16 patients (31.25%), bilaterally in 3 of them. Among the five patients with sentinel node metastasis, this was the only tumor positive lymph node in one patient. In all cases with negative dynamic sentinel node biopsy, no metastatic nodes were found at the following inguinal node dissection. Therefore, the technique showed a 100% negative predictive value and an 88% sensitivity. Conclusions We believe that dynamic sentinel node biopsy is a minimally invasive procedure that can be easily performed. The goal is to offer the possibility of less extensive surgery for selected low risk patients. J. Surg. Oncol. 2006;93: 181–185. © 2006 Wiley‐Liss, Inc.