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Inguinal canal as an anatomic sanctuary site of relapse in peritoneal carcinomatosis previously treated with intraperitoneal chemotherapy
Author(s) -
Liberale Gabriel,
Elias Dominique,
Sideris Lucas,
Lasser Philippe,
Malka David,
Sabourin JeanChristophe,
Pocard Marc
Publication year - 2005
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/jso.20267
Subject(s) - medicine , intraperitoneal chemotherapy , peritoneal carcinomatosis , surgery , chemotherapy , perioperative , cytoreductive surgery , peritoneal cavity , carcinosis , abdominal cavity , spermatic cord , cancer , colorectal cancer , ovarian cancer
Early postoperative intraperitoneal chemotherapy (EPIC) and intraoperative peritoneal hypertermic chemotherapy (IPHC) are used in addition with cytoreductive surgery to treat with curative intent peritoneal carcinomatosis arising from colorectal adenocarcinomas. Three patients with such a disease were treated with perioperative intraperitoneal chemotherapy in addition to cytoreductive surgery and presented isolated local recurrence located in the inguinal canal (round ligament in two and spermatic cord in one). All these patients were treated by local surgical excision. No patient showed evidence of intra‐abdominal recurrence at the last follow‐up, but one developed pulmonary metastasis. When communicating with the peritoneal cavity, the inguinal canal may act as a sanctuary site for peritoneal carcinomatosis, since it is not totaly soaked by the intraperitoneal chemotherapy solution. A local recurrence is thus possible. New clinical presentations such as this one have first to be described in order to improve patient follow‐up. J. Surg. Oncol. 2005;91:73–76. © 2005 Wiley‐Liss, Inc.