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Enhancement of the water solubility and antioxidant activity of hesperidin by chitooligosaccharide
Author(s) -
Cao Ruge,
Zhao Yali,
Zhou Zhongkai,
Zhao Xiaoyu
Publication year - 2018
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.8734
Subject(s) - hesperidin , solubility , antioxidant , chemistry , nuclear chemistry , thermogravimetric analysis , fourier transform infrared spectroscopy , chromatography , organic chemistry , chemical engineering , medicine , alternative medicine , pathology , engineering
BACKGROUND Hesperidin is a natural product and a strong antioxidant with potential applications in various food and pharmaceutical products. However, its poor water solubility greatly limits its applications. RESULTS In this study, chitooligosaccharide (COS) was applied to prepare a stable complex with hesperidin (Hesp‐COS) via the spray‐drying method at 100 °C for 20 min. The resultant complex was characterized by Fourier transformation infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy and proton nuclear magnetic resonance spectroscopy. It was demonstrated that the aromatic rings of hesperidin interacted with COS through hydrogen bonding and formed Hesp‐COS complex. As a result, both the water solubility and antioxidant activity of Hesp‐COS were higher than that of the free hesperidin. CONCLUSION The preparation conditions of Hesp‐COS in this study were efficient and produced an increment in both the water solubility and antioxidant activity of hesperidin. © 2017 Society of Chemical Industry