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Effect of prebiotics of Agave salmiana fed to healthy Wistar rats
Author(s) -
JassoPadilla Iliana,
JuárezFlores Bertha,
AlvarezFuentes Gregorio,
CruzMartínez Alejandro,
GonzálezRamírez José,
MoscosaSantillán Mario,
GonzálezChávez Marco,
OrosOvalle Cuauhtemoc,
Prell Florian,
Czermak Peter,
MartinezGutierrez Fidel
Publication year - 2016
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.7764
Subject(s) - fructan , inulin , bifidobacterium animalis , prebiotic , food science , lactobacillus , agave , bifidobacterium , biology , chemistry , sucrose , fermentation , botany
BACKGROUND Inulin and other fructans are synthesized and stored in mezcal agave ( Agave salmiana ). Fructans provide several health benefits and have excellent technological properties, but only few data report their physiological effect when added in the diet. RESULTS Here, we studied the physiological effects of fructans obtained from A. salmiana when added in the diet of Wistar rats. Results showed favorable changes on Wistar rats when the fructans was added to their diet, including the decrease of the pH in the feces and the increase of the number of lactic acid bacteria ( CFU g −1 ) ( Lactobacillus spp. and Bifidobacterium spp.), even these changes were enhanced with the synbiotic diet (fructans plus B. animalis subsp. lactis ). Synbiotic diet, developed changes in the reduction of cholesterol and triglycerides concentrations in serum, with statistical differences ( P < 0.05). Histological analysis of colon sections showed that synbiotic diet promoted colon cells growth suggesting that fructans from A. salmiana confer beneficial health effects through gut microbiota modulation. CONCLUSION Our data underline the advantage of targeting the gut microbiota by colonic nutrients like specific structure of fructans from A. salmiana , with their beneficial effects. More studies are necessary to define the role of fructans to develop more solid therapeutic solutions in humans. © 2016 Society of Chemical Industry