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Exposure assessment of dogs to mycotoxins through consumption of dry feed
Author(s) -
Bissoqui Lucas Y,
Frehse Michele S,
Freire Roberta L,
Ono Mario A,
Bordini Jaqueline G,
Hirozawa Melissa T,
de Oliveira Andressa J,
Ono Elisabete YS
Publication year - 2016
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.7615
Subject(s) - zearalenone , mycotoxin , aflatoxin , zoology , toxicology , food science , exposure assessment , tolerable daily intake , food contaminant , body weight , biology , medicine , environmental health , endocrinology
BACKGROUND The Brazilian exportation of pet food has shown high growth rates in the last two years and determination of the exposure degree is one of the most important parameters for the risk assessment of chemical compounds. In this study the exposure degree of dogs to mycotoxins was estimated and acceptable daily intake ( ADI ) and safe pet dietary level ( SPDL ) were calculated. Thus the natural occurrence of fumonisins, zearalenone and aflatoxins was evaluated in 100 dry dog feed samples provided by pet owners in Paraná State, Brazil. RESULTS Despite the high frequency of fumonisins (68%), zearalenone (95%) and aflatoxins (68%) in feed samples, the mean levels detected were low. ADI for fumonisins and zearalenone was 20.0 and 1.00 µg kg −1 body weight ( BW ) day −1 respectively and SPDL for fumonisins was 2000 µg kg −1 feed. The probable daily intake values (1.83 µg fumonisins, 0.93 µg zearalenone and 0.02 µg aflatoxins kg −1 BW day −1 ) were low. CONCLUSION The exposure degree of dogs could be assumed to be very low. However, the co‐occurrence of these three or other mycotoxins, and possible synergic or additive effects, should be taken into account when determining the maximum allowed levels or risk assessment. © 2016 Society of Chemical Industry