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Metabolomic applications in nutritional research: a perspective
Author(s) -
O'Gorman Aoife,
Brennan Lorraine
Publication year - 2015
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.7070
Subject(s) - metabolomics , biomarker , identification (biology) , computational biology , microbiology and biotechnology , bioinformatics , medicine , biology , chemistry , biochemistry , botany
Metabolomics focuses on the global study of metabolites in cells, tissues and biofluids. Analytical technologies such as nuclear magnetic resonance ( NMR ) spectroscopy and hyphenated mass spectrometry ( MS ) combined with advanced multivariate statistical methods allow us to study perturbations in metabolism. The close link between metabolism and nutrition has seen the application of metabolomics in nutritional research increase in recent times. Such applications can be divided into three main categories, namely (1) the area of dietary biomarker identification, (2) diet‐related diseases and (3) nutritional interventions. The present perspective gives an overview of these applications and an outlook to the future. © 2015 Society of Chemical Industry