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Retracted : Properties and stability of blueberry anthocyanin – bovine serum albumin nanoparticles
Author(s) -
Chen Jian,
Tao Xiaoyun,
Zhang Meng,
Sun Aidong,
Zhao Liyi
Publication year - 2014
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.6492
Subject(s) - anthocyanin , bovine serum albumin , chemistry , nanocarriers , nanoparticle , chromatography , biochemistry , food science , organic chemistry , nanotechnology , drug delivery , materials science
BACKGROUND Since they would be easily decomposed under alkaline conditions, anthocyanins are likely to have poor oxidation stability. However, encapsulated with protein molecules, anthocyanins could be protected owing to the slowing down of the oxidation process. In this study, the characteristics of nanoparticles, formed by the interactions of anthocyanins with bovine serum albumin ( BSA ), and their impact on the oxidation stability of anthocyanins were investigated.RESULTS Both BSA and anthocyanin‐bound BSA could form self‐assembled nanoparticles in phosphate buffer ( pH 7.4), and the particle size of anthocyanin‐bound BSA (20–25 nm) was smaller than that of BSA (35–40 nm). The ratio of BSA to anthocyanin was 1:10. The radical scavenging rates of BSA ‐bound anthocyanin were lower than those of the unbound anthocyanin. No significant difference was seen in the stability between the unbound and BSA ‐bound anthocyanin in the simulated gastric system, whereas a difference was seen in the simulated intestinal system. The amount of unbound anthocyanin decreased by 70% after 6 h, while BSA ‐bound anthocyanin was almost unchanged. BSA exhibited a remarkable effect on the oxidation stability of anthocyanins.CONCLUSION BSA nanocarriers could improve the stability of anthocyanin under neutral conditions, which has great potential for applications. © 2013 Society of Chemical Industry