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Effects of individual and combined administration of ochratoxin A and aflatoxin B 1 in tissues and eggs of White Leghorn breeder hens
Author(s) -
Hassan Zahoor Ul,
Khan Muhammad Z,
Khan Ahrar,
Javed Ijaz,
Hussain Zahid
Publication year - 2012
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.4740
Subject(s) - ochratoxin a , mycotoxin , aflatoxin , ochratoxin , zoology , zearalenone , toxin , food science , biology , ochratoxins , animal feed , food contaminant , chemistry , biochemistry
BACKGROUND: Mycotoxins, the secondary fungal metabolites, are unavoidable contaminants of human and animal food and feeds. The objectives of this study were to evaluate the effect of concurrent feeding of ochratoxin A (OTA) and aflatoxin B 1 (AFB 1 ) to breeder hens, upon their deposition in different tissues and eggs. RESULTS: Residues of OTA and AFB 1 in (ng g −1 ) were significantly higher in liver followed by kidneys and breast muscles by 22.54 ± 1.48, 4.22 ± 0.93 and 0.56 ± 0.06 for OTA (group fed OTA at 5 mg kg −1 diet) and 1.44 ± 0.21, 0.25 ± 0.01 and 0.03 ± 0.01 for AFB 1 (group fed AFB 1 at 5 mg kg −1 diet), respectively. Residues of OTA and AFB 1 in eggs appeared at days 3 and 5 of toxin feeding and disappeared at days 5 and 6 of withdrawal of mycotoxins contaminated feed, respectively. The residues of OTA and AFB 1 were significantly lower in the tissues of hens fed these toxins concurrently compared with the groups fed OTA and AFB 1 independently. CONCLUSIONS: Residues of OTA and AFB 1 appeared in the tissues and eggs of laying hens kept on OTA‐ and AFB 1 ‐contaminated diets. Concurrent feeding of OTA and AFB 1 to hens significantly decreased the concentration of OTA and AFB 1 residues in the tissues and eggs. Copyright © 2011 Society of Chemical Industry