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Effect of pre‐germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats
Author(s) -
Roohinejad Shahin,
Omidizadeh Alireza,
Mirhosseini Hamed,
Saari Nazamid,
Mustafa Shuhaimi,
Mohd Yusof Rokiah,
Meor Hussin Anis Shobirin,
Hamid Azizah,
Abd Manap Mohd Yazid
Publication year - 2009
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.3803
Subject(s) - brown rice , germination , cholesterol , food science , serum cholesterol , biology , chemistry , endocrinology , botany
BACKGROUND: Brown rice is unpolished rice with immeasurable benefits for human health. Brown rice (BR) and pre‐germinated brown rice (PGBR) are known to contain various functional compounds such as γ‐oryzanol, dietary fibre and γ‐aminobutyric acid (GABA). In the present study, the experimental diets containing BR and PGBR (24, 48 h pre‐germination) were used to investigate the influence of pre‐germination time of brown rice on blood cholesterol in Sprague–Dawley male rats. RESULTS: Hypercholesterolaemia and elevation of LDL‐cholesterol were successfully ameliorated by the experimental diets containing BR and PGBR (24 and 48 h pre‐germination). As compared to the control sample, the pre‐germination time had a significant ( P < 0.05) effect on blood cholesterol of Sprague–Dawley male rats. It was also found that the significantly ( P < 0.05) better effect on lipid profile of hypercholesterolaemic rats was observed by prolonging the pre‐germination time. As compared to non‐germinated brown rice, the germinated brown rice showed the higher cardio‐protective effect on hypercholesterolaemic Sprague–Dawley male rats. CONCLUSION: The present study suggests that the changes of blood cholesterol can be mainly modulated by using the PGBR rather than BR. The prolonging of pre‐germination time led to an increase in the bioactive components, thereby providing a more efficient functional diet affecting the high blood cholesterol. This study suggests that PGBR can be used instead of BR and polished rice in the human diet. Copyright © 2009 Society of Chemical Industry