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Effect of pectin on plasma lipids and caecal enzyme activity in rutin‐supplemented mice
Author(s) -
Tamura Motoi,
Hirayama Kazuhiro,
Itoh Kikuji
Publication year - 2009
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.3571
Subject(s) - rutin , pectin , quercetin , caecum , triglyceride , cholesterol , food science , chemistry , lipid metabolism , enzyme , cecum , biology , biochemistry , medicine , antioxidant , ecology
BACKGROUND: Few previous reports have considered the effects of dietary fibre on the plasma lipids and caecal enzyme activity of mice fed a rutin‐supplemented diet. This investigation studied the effects of pectin on the plasma lipids and caecal enzyme activities of mice fed a diet supplemented with the quercetin glycoside rutin. RESULTS: Male mice were randomly divided into two groups and fed either a pectin–rutin (PR) diet or a cellulose–rutin (CR) diet for 14 days. Plasma cholesterol and triglyceride concentrations and caecal β‐glucosidase and β‐glucuronidase activities were measured. The plasma cholesterol and triglyceride concentrations were significantly higher in the CR diet group, as were the caecal β‐glucosidase and β‐glucuronidase activities. The caecal β‐glucuronidase/β‐glucosidase activity ratio was significantly higher in the PR diet group, indicating differences in the metabolic activity of the intestinal flora. CONCLUSION: The PR diet greatly affected the caecal enzyme activities. A pectin diet supplemented with the quercetin glycoside rutin might affect the lipid metabolism and metabolic activity of the intestinal flora. The plasma lipid‐lowering effects of the PR diet might have been partially caused by the metabolic actions of the intestinal gut flora. Copyright © 2009 Society of Chemical Industry