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Effects of defatted dried roselle ( Hibiscus sabdariffa L.) seed powder on lipid profiles of hypercholesterolemia rats
Author(s) -
Hainida Emmy,
Ismail Amin,
Hashim Normah,
Mohd.Esa Norhaizan,
Zakiah Ainul
Publication year - 2008
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.3186
Subject(s) - hibiscus sabdariffa , cholesterol , food science , chemistry , zoology , lipid profile , ldl cholesterol , biology , biochemistry
BACKGROUND: In vivo investigations were made of the effect of defatted dried roselle seed powder (DRS) on the lipid profiles of rats with induced hypercholesterolemia. The two‐batch sample consisted of 23 and 20 Sprague‐Dawley male rats randomly divided into four groups and fed with four different diets. The first batch of rats was fed with normal, hypercholesterol, hypercholesterol + 10 g kg −1 (w/w) DRS and hypercholesterol + 20 g kg −1 (w/w) DRS diets. The second batch of rats was fed with normal, hypercholesterol, hypercholesterol + 50 g kg −1 (w/w) DRS and hypercholesterol + 150 g kg −1 (w/w) DRS diets. Treatments were given for a total of 5 weeks. RESULTS: Results indicated that the addition of 10 g kg −1 and 20 g kg −1 of DRS did not significantly lower the plasma total cholesterol (TC) levels. In contrast, 50 g kg −1 and 150g kg −1 DRS significantly lowered ( P < 0.05) the TC and low density lipoprotein cholesterol (LDL‐C) levels. CONCLUSION: The addition of 50 g kg −1 and 150 g kg −1 DRS showed potential hypocholesterolemic effects. Furthermore, these findings indicated that protein, lipid and dietary fibre were high in the seed powder. Copyright © 2008 Society of Chemical Industry