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Anti‐sickling potential of Aloe vera extract
Author(s) -
Ejele Agunna Everest,
Njoku Pascal Chukwuemeka
Publication year - 2008
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.3036
Subject(s) - aloe vera , in vitro , traditional medicine , chemistry , pharmacology , biology , medicine , biochemistry
The effect of Aloe vera extract on the gelling time of human HbSS erythrocytes was investigated. The results showed that A. vera extract increased the gelling time of HbSS blood and inhibited sickling in vitro . In addition, a linear relationship was found between extract concentration and gelling time, suggesting that A. vera extract may have great potential in the management of sickle cell disease. Copyright © 2008 Society of Chemical Industry