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Mutagenicity of chemicals of industrial and agricultural relevance in Salmonella, streptomyces and Aspergillus
Author(s) -
Principe Paola,
Dogliotti Eugenia,
Bignami Margherita,
Crebelli Riccardo,
Falcone Emiliana,
Fabrizi Maria,
Conti Giuseppe,
Comba Pietro
Publication year - 1981
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740320812
Subject(s) - streptomyces coelicolor , aspergillus nidulans , salmonella , mutagen , chemistry , ethylene , alcohol , ames test , microbiology and biotechnology , biochemistry , biology , gene , bacteria , carcinogen , genetics , mutant , catalysis
Abstract Five chemicals of industrial and agricultural relevance—ethylene dibromide, ethylene dichloride, propylene dichloride, allyl alcohol and sulphallate—were tested for their ability to induce reverse mutations in Salmonella typhimurium and forward mutations in Streptomyces coelicolor and Aspergillus nidulans . Ethylene dibromide was positive in all the genetic systems employed; sulphallate gave a positive response, to different degrees, in all the microorganisms; ethylene dichloride was weakly active in S. typhimurium following microsomal activation; propylene dichloride was detected as a direct acting mutagen in S. typhimurium and A. nidulans but not in S. coelicolor; allyl alcohol was completely negative in all test systems.