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The source of androgenic activity in the African wood Funtumia latifolia : A steroid hormone formed by the action of fusarium solani
Author(s) -
Smith Anthony J.,
Wells John W.
Publication year - 1978
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740290907
Subject(s) - fusarium solani , fusarium , metabolite , steroid , biology , fungus , antifungal , botany , hormone , microbiology and biotechnology , biochemistry
The wood of an African tree Funtumia latifolia had androgenic properties when mixed with diets fed to chicks. The androgenic principle has been identified tentatively as an hydroxyandrosta‐1,4‐dienedione but it is not identical with 12β‐hydroxyandrosta‐1,4‐diene‐3,17‐dione isolated previously from the leaves of a Halorrhena species in Cameroun or as a microbial metabolite of deoxycholic acid. The androgen is formed by metabolism of the steroidal alkaloids in F. latifolia by the saprophytic fungus Fusarium solani .