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Isolation of an organoarsenic compound present in cod liver
Author(s) -
Lunde Gulbrand
Publication year - 1975
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740260902
Subject(s) - chemistry , dimethylformamide , hydrolysis , organic chemistry , aqueous solution , infrared spectroscopy , water soluble , arsenic , size exclusion chromatography , chromatography , nuclear chemistry , solvent , enzyme
By methods based on ion exchange, liquid extraction, gel filtration and thinlayer chromatography, an extract of marine origin has been prepared that contains close to 100% (on dry weight basis) of a water‐soluble organoarsenic compound. As starting material an aqueous extract prepared by enzymic hydrolysis of defatted cod liver has been used. The arsenic compound has been further characterised by i.r. and u.v. spectroscopy. Attempts have also been made at making derivatives of the compound. The organoarsenic compound has a strong absorption at about 260 nm. It also has an infrared spectrum showing aromatic characteristics and hydroxyl‐ and amino functions. By reaction with bistrimethylsilyltrifluoracetamide (BSTFA) the water‐soluble organoarsenic compound is converted to a compound that is soluble in organic solvents. By methylating (dimethylformamide‐diethylacetal) the compound becomes less polar, but is still partly soluble in water.