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Simultaneous analysis of 2,3,4,6‐tetrachloroanisole, pentachloroanisole and the corresponding chlorophenols in biological tissue
Author(s) -
Gee Malcolm G.,
Land Derek G.,
Robinson David
Publication year - 1974
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740250712
Subject(s) - extraction (chemistry) , chromatography , electron capture detector , chemistry , gas chromatography , muscle tissue , biology , anatomy
A method has been developed for the analysis of 2,3,4,6‐tetrachloro‐ and pentachloroanisoles and the corresponding chlorophenols in biological extracts. Ethylation followed by separation of the preformed anisoles from the corresponding phenetoles (ethyl phenyl ethers) by gas chromatography using an electron capture detector provides a sensitive method of analysis. The extraction method of Likens and Nickerson, whilst satisfactory for the chloroanisoles in all the samples investigated, was not adequate for quantitative recovery of chlorophenols from muscle or fatty tissue. An alternative extraction method, not applicable to chloroanisoles, was satisfactory for muscle but was not suitable for skin or fatty tissue.