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Effects of protein intake on the storage of copper in the liver of sheep
Author(s) -
Macpherson A.,
Hemingway R. G.
Publication year - 1965
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740160408
Subject(s) - copper , meal , chemistry , zoology , basal (medicine) , biology , food science , endocrinology , organic chemistry , insulin
Death from copper poisoning resulting from administration of 1·0 g. of CuSO 4 ,5H 2 O per day occurred after periods ranging from 10 to 34 weeks in two groups of housed sheep on concentrate diets containing 10 and 20% of protein, respectively. The additional protein was dried blood meal. Those on the higher protein intake appeared to be the more resistant, although the concentration of copper in the liver of both groups were in the dangerously high range. Rather less than 3% of the supplementary copper was stored in the liver. Additional protein did not affect copper storage when sheep on basal diets providing 10% of protein and containing about 6 p.p.m. of Cu were supplemented with 10 mg. of Cu per day.