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The nature of some of the linkages in deoxypentose nucleic acids
Author(s) -
Overend W. G.,
Peacocke A. R.,
Stacey M.
Publication year - 1952
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740030302
Subject(s) - nucleic acid , dna , branching (polymer chemistry) , glycosidic bond , chemistry , biochemistry , stereochemistry , organic chemistry , enzyme
Abstract Knowledge of the linkages in deoxyribonucleic acids is reviewed and extended. Chromatographic analyses and electrometric titrations on deoxyribonucleic acids isolated from various sources indicate a greater degree of branching than has been previously assumed. Available evidence on the nature of hydrogen bonding in these nucleic acids is surveyed. Evidence for the possible existence of a highly labile glycosidic linkage is presented. The action of dilute alkali under mild conditions on deoxyribonucleic acids, as described by Euler & Fono (1948), is reinterpreted.