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A mode of action of antibiotics in chick nutrition
Author(s) -
Coates M. E.,
Dickinson C. D.,
Harrison G. F.,
Kon S. K.,
Porter J. W. G.,
Cummins S. H.,
Cuthbertson W. F. J.
Publication year - 1952
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.2740030108
Subject(s) - penicillin , procaine , antibiotics , biology , microbiology and biotechnology , food science , pharmacology
Procaine penicillin [penicillin (procaine salt)] added to a good practical ration improved the growth of chicks in a laboratory used for poultry for ten years. Chicks from the same batch in two other laboratories, where birds had not been kept before, grew equally well on the ration with and without penicillin, and growth was the same as that on the penicillinsupplemented diet in the usual chick laboratory. The growth depression in the absence of dietary penicillin was not due to differences in management or to recognizable disease. It is suggested that it is due to an ‘infection’ hitherto undescribed and shown to be transmissible and counteracted by penicillin.