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Inhibition of streptococcal biofilm formation by Aronia by extracellular RNA degradation
Author(s) -
Lee HeonJin,
Oh Su Young,
Hong SuHyung
Publication year - 2020
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/jsfa.10223
Subject(s) - biofilm , chemistry , microbiology and biotechnology , food science , extracellular polymeric substance , bacteria , biology , genetics
BACKGROUND The accumulation of oral bacterial biofilms is one of the primary etiological factors for oral diseases. Aronia melanocarpa extracts display general health benefits, including antimicrobial activities. This study evaluates the inhibitory effect of Aronia juice on oral streptococcal biofilm formation. RESULTS Exposure to 1/10‐diluted Aronia juice for 1 min significantly decreased in vitro streptococcal biofilm formation ( P < 0.001). No remarkable difference was noted in streptococcal growth by Aronia under the same conditions. Interestingly, 1 week of oral rinse with diluted Aronia juice led to significantly fewer salivary streptococcal colony‐forming units (CFUs) relative to oral rinsing with tap water ( P < 0.05). Furthermore, Aronia exerted an extracellular RNA‐degrading effect, and RNase inhibitor alleviated Aronia ‐dependent streptococcal biofilm inhibition. CONCLUSION Aronia might inhibit initial biofilm formation by decomposing extracellular RNA, which plays an important role in bacterial biofilm formation. Our data suggest that oral rinsing with Aronia juice will aid in treating oral biofilm‐dependent diseases easily and efficiently. © 2019 Society of Chemical Industry