Premium
Eliminating irreproducibility in SERS substrates
Author(s) -
Grys DavidBenjamin,
Chikkaraddy Rohit,
Kamp Marlous,
Scherman Oren A.,
Baumberg Jeremy J.,
Nijs Bart
Publication year - 2021
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.6008
Subject(s) - raman spectroscopy , surface enhanced raman spectroscopy , nanotechnology , substrate (aquarium) , field (mathematics) , reproducibility , computer science , materials science , biochemical engineering , chemistry , raman scattering , optics , engineering , physics , mathematics , chromatography , geology , oceanography , pure mathematics
Irreproducibility in surface‐enhanced Raman spectroscopy (SERS) due to variability among substrates is a source of recurrent debate within the field. It is regarded as a major hurdle towards the widespread adoption of SERS as a sensing platform. Most of the literature focused on developing substrates for various applications considers reproducibility of lower importance. Here, we address and analyse the sources of this irreproducibility in order to show how these can be minimised. We apply our findings to a simple substrate demonstrating reproducible SERS measurements with relative standard deviations well below 1% between different batches and days. Identifying the sources of irreproducibility and understanding how to reduce these can aid in the transition of SERS from the lab to real‐world applications.