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Thiol‐modified gold‐coated glass as an efficient hydrophobic substrate for drop coating deposition Raman (DCDR) technique
Author(s) -
Kočišová Eva,
Procházka Marek,
Šípová Hana
Publication year - 2016
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.4961
Subject(s) - raman spectroscopy , substrate (aquarium) , layer (electronics) , materials science , coating , drop (telecommunication) , chemical engineering , nanotechnology , composite material , optics , telecommunications , oceanography , physics , engineering , geology , computer science
In this paper we report an easy and low‐cost way to prepare a hydrophobic substrate for drop coating deposition Raman (DCDR) spectroscopy. This substrate is formed by a thiol‐modified Au‐coated glass and provides the Raman spectra with the same quality as the commercial Teflon‐coated stainless steel substrate (SpectRIM™, Tienta Sciences, Inc.) for model molecular systems – albumin solution and liposome suspension. Gold layer, similarly to polished steel in the commercial substrate, served as a highly refractive layer strongly increasing the Raman signal. The main advantage of introduced substrate is that it is simple and a low‐cost preparation easily manageable in every standard laboratory. Thus, it represents a promising alternative to commercial Teflon‐coated stainless steel substrate. Copyright © 2016 John Wiley & Sons, Ltd.

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