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Hydrogen bonding dynamics of cyclodextrin–water solutions by depolarized light scattering
Author(s) -
Rossi B.,
Comez L.,
Fioretto D.,
Lupi L.,
Caponi S.,
Rossi F.
Publication year - 2011
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.2885
Subject(s) - chemistry , hydrogen bond , aqueous solution , cyclodextrin , molecule , solvent , raman scattering , relaxation (psychology) , raman spectroscopy , chemical physics , characterization (materials science) , molecular dynamics , light scattering , dynamic light scattering , crystallography , computational chemistry , scattering , organic chemistry , nanotechnology , materials science , psychology , social psychology , physics , optics , nanoparticle
Abstract Depolarized light scattering measurements performed on aqueous solutions of α‐cyclodextrin are used for investigating the hydration properties of this natural cyclic oligosaccharide, which is well known for its ability to form inclusion complexes with a large variety of guest hydrophobic molecules. The spectral analysis allows the characterization of the solvent relaxation process assigned to hydration water, which is found to be seven to eight times slower than the bulk. As a structural information, the number of water molecules involved in the hydration process is also estimated at about 46. These results are a key step for understanding the role played by water in determining the properties of different forms of cyclodextrins and their derivatives, in turn related to complexation ability of these macrocycles. Copyright © 2011 John Wiley & Sons, Ltd.