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Observation of SERS effect in Raman optical activity, a new tool for chiral vibrational spectroscopy
Author(s) -
Abdali Salim
Publication year - 2006
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1541
Subject(s) - raman optical activity , raman spectroscopy , molecule , chemistry , chirality (physics) , spectroscopy , analytical chemistry (journal) , pentapeptide repeat , surface enhanced raman spectroscopy , molecular vibration , chemical physics , raman scattering , optics , organic chemistry , peptide , chiral symmetry , biochemistry , physics , quantum mechanics , nambu–jona lasinio model , quark
A new tool for chiral vibrational spectroscopy is reported here. A surface enhanced effect was observed using Raman optical activity (ROA). This observation opens new possibilities for ROA as a tool for vibrational spectroscopy. The combination of surface enhanced effect (SE) and ROA into surface enhanced Raman optical activity (SEROA) takes this tool to another level, where a single molecule may be studied with respect to chirality, secondary structure and fold determination. ROA has been able to provide information about important dynamics in molecular understanding. Until recently, however, ROA measurements required a longer exposure and higher concentration of the sample. With SEROA these obstacles can be overcome because both studies on single molecule, i.e. very low concentration, and faster acquisition of the signal can be carried out. In the present, work silver colloids were mixed with solution, in which a pentapeptide, Met‐Enkephalin, was dissolved. SEROA signals were recorded and the results are reported here. Copyright © 2006 John Wiley & Sons, Ltd.