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Vibrational Raman optical activity of simple amino acids
Author(s) -
Gargaro A. R.,
Barron L. D.,
Hecht L.
Publication year - 1993
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1250240206
Subject(s) - raman spectroscopy , raman optical activity , simple (philosophy) , chemistry , optics , physics , philosophy , epistemology
The vibrational Raman optical activity (ROA) spectra of the simple amino acids L ‐serine, L ‐cysteine, L ‐valine, L ‐threonine and L ‐isoleucine in aqueous solution between 600 and 1600 cm −1 measured in backscattering are presented and discussed. Complete vibrational assignments are suggested for serine and cysteine and limited assignments for the others. Bands originating in C α *H deformations and the symmetric CO 2 − stretch appear to provide the best signatures for stereochemical studies. The results show that ROA provides a new perspective on amino acid conformation in aqueous solution.