Premium
Surface‐enhanced Raman analysis of vitamin B complex: Quantitative detection of p ‐aminobenzoic acid
Author(s) -
Narayanan V. Anantha,
Bello Job M.,
Stokes David L.,
VoDinh Tuan
Publication year - 1991
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1250220605
Subject(s) - raman scattering , p aminobenzoic acid , raman spectroscopy , chemistry , substrate (aquarium) , calibration curve , vitamin , analytical chemistry (journal) , detection limit , chromatography , optics , biochemistry , physics , oceanography , geology
Surface‐enhanced Raman scattering (SERS) spectra of vitamin B complex extracted in ethanol were analyzed using a silver‐coated alumina substrate. The SERS effect appears to enhance selectively the spectrum of p ‐aminobenzoic acid (PABA) from among the complex constituents of the vitamin B complex tablet. A calibration graph of SERS signal intensity versus concentration of PABA was constructed for quantitative analysis. With such a graph it is possible to detect PABA down to low parts per million levels. The potential of the SERS technique in other analytical and biomedical areas is discussed.