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Detection of calcific deposits in atherosclerotic lesions by laser Raman spectroscopy
Author(s) -
Clarke R. H.,
Hanlon E. B.,
Brody H.,
Isner J. M.
Publication year - 1988
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1250190308
Subject(s) - raman spectroscopy , calcification , laser , materials science , calcinosis , chemistry , medicine , optics , physics
The laser Raman scattering from calcified regions of diseased cardiovascular tissue samples dissected from the coronary arteries and aortic valves was measured. The spectra reveal the characteristic vibrational features of the phosphate grouping in the solid state. Spectral features for the calcified artery segments and aortic valves are compared for details of the chemical and structural makeup of the calcific lesions.