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Resonance Raman studies of guanine derivatives
Author(s) -
Chinsky L.,
Jollès B.,
Laigle A.,
Turpin P. Y.
Publication year - 1987
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1250180309
Subject(s) - raman spectroscopy , guanine , guanosine , chemistry , resonance (particle physics) , imidazole , pyrimidine , resonance raman spectroscopy , crystallography , stereochemistry , photochemistry , computational chemistry , nucleotide , biochemistry , physics , atomic physics , optics , gene
Abstract Ultraviolet resonance Raman spectra of some guanine derivatives in aqueous solutions are reported, viz. guanosine, N 1 ‐methylguanosine, N 2 ‐methylguanosine and N 2 , N 2 ‐dimethylguanosine. The effects of deuteriation were also investigated. The vibrational patterns of guanosine and the derivatives are complicated, since they involve contributions from both the pyrimidine and imidazole rings. However, the understanding of the spectral features is of special interest since some bands are highly sensitive to the B to Z conformational transition of alternating dG‐dC sequences containing DNA. From these UV resonance Raman spectra, assignments of the principal modes of vibration are proposed and discussed in relation to the results of normal coordinate calculations previously performed by other workers.