Premium
Raman and infrared spectra of spermidine and spermine and their hydrochlorides and phosphates as a basis for the study of the interactions between polyamines and nucleic acids
Author(s) -
Bertoluzza A.,
Fagnano C.,
Finelli P.,
Morelli M. A.,
Simoni R.,
Tosi R.
Publication year - 1983
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1250140606
Subject(s) - raman spectroscopy , spermine , nucleic acid , chemistry , spermidine , hydrogen bond , polyamine , infrared spectroscopy , infrared , stereochemistry , organic chemistry , biochemistry , enzyme , molecule , physics , optics
The Raman and infrared spectra of the polyamines spermidine and spermine and of their corresponding hydrochlorides and phosphates have been studied. These systems can be regarded as models of the molecular interactions between polyamines and nucleic acids, and the observed spectra are discussed in relation to this. Medium strong and strong NHCl and NHO hydrogen bonds are present in both the polyamine hydrochlorides and phosphates and the proton is predominantly located on the nitrogen atom. In the case of the phosphates, the Raman spectra indicate the formation of HPO 4 2−groups, which can also interact among themselves by strong OHO hydrogen bonds.