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Raman studies of platinum‐nucleoside complexes
Author(s) -
Theophanides T.,
Hadjiliadis N.,
Berjot M.,
Manfait M.,
Bernard L.
Publication year - 1976
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1250050403
Subject(s) - raman spectroscopy , inosine , guanosine , platinum , chemistry , nucleoside , solid state , metal , inorganic chemistry , crystallography , stereochemistry , organic chemistry , biochemistry , optics , physics , enzyme , catalysis
The laser Raman spectra of a new series of platinum‐nucleoside complexes have been studied in solution at physiological pH values and in the solid state as powders. A qualitative analysis of certain vibrational modes responsible for various spectral lines is given. The carbonyl stretching frequency of guanosine and inosine is only slightly perturbed in the solid state whereas it is not affected at all upon coordination of the metal in water solutions. It is suggested that the binding of the free bases takes place at the Pt‐N 7 site in all these complexes.