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Identification and characterization of pharmaceuticals using Raman and surface‐enhanced Raman scattering
Author(s) -
Cîntǎ Pînzaru S.,
Pavel I.,
Leopold N.,
Kiefer W.
Publication year - 2004
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1153
Subject(s) - raman spectroscopy , raman scattering , characterization (materials science) , excipient , adsorption , chemistry , nanotechnology , fourier transform , analytical chemistry (journal) , materials science , organic chemistry , chromatography , optics , physics , quantum mechanics
Many recent papers reflect ongoing research and development concerning pharmaceutical applications of Raman techniques. This short review highlights different Raman techniques (dispersive, Fourier transform, resonance Raman, SERS, SERRS, FT‐SERS) employed in pharmaceutical investigations. Several Raman applications such as fundamental structural investigations, quantitative analysis, drug–excipient interaction, formulation, limit of detection, pH‐dependent pharmaceutical species, adsorption geometry at a given surface and functional groups involved in adsorption for several widely used pharmaceutical compounds are presented. Copyright © 2004 John Wiley & Sons, Ltd.