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Fourier transform Raman spectroscopy of drugs: quantitative analysis of 1‐phenyl‐2,3‐dimethyl‐5‐pyrazolone‐4‐methylaminomethane sodium sulfonate: (dipyrone)
Author(s) -
Izolani Antônio O.,
de Moraes Milena T.,
Téllez S. Claudio A.
Publication year - 2003
Publication title -
journal of raman spectroscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.748
H-Index - 110
eISSN - 1097-4555
pISSN - 0377-0486
DOI - 10.1002/jrs.1064
Subject(s) - raman spectroscopy , chemistry , fourier transform , fourier transform infrared spectroscopy , analytical chemistry (journal) , quantitative analysis (chemistry) , chromatography , mathematics , physics , optics , mathematical analysis
Several drugs provided by the pharmaceutical industry and containing dipyrone as the active principle have different mass percentages of the letter. We describe a procedure for the quantitative analysis of several tablets containing dipyrone (or other solid active principles). The results of Fourier transform Raman band analysis (band area and band height) agree well with the stated contents of dipyrone in the tablets. Copyright © 2003 John Wiley & Sons, Ltd.