Open AccessExtravasation of High‐Dose Methotrexate A Case about Nothing
Author(s) -
Ang TzinSiu,
Siderov Jim
Publication year - 1998
Publication title -
the australian journal of hospital pharmacy
Language(s) - English
Resource type - Journals
ISSN - 0310-6810
DOI - 10.1002/jppr1998286430
Subject(s) - extravasation , methotrexate , medicine , chemotherapy , pharmacology , surgery , pathology
The effective management of cytotoxic drug extravasation is limited by the lack of published data on which to base treatments. Methotrexate (MTX) is an antineoplastic agent used in a wide variety of tumours. However, there are no published data on the sequelae from extravasation of high‐dose MTX. These two case reports give some insight into the sequelae from high‐dose MTX extravasation, and some guidance on treatment.