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Streptokinase and streptokinase card: questionnaire validation to evaluate knowledge among post‐STEMI patients in a Malaysian Tertiary Hospital
Author(s) -
Ang Wei Chern,
Ibrahim Arief,
Mohd Puad Norfarazila,
Abd Karim Nur Amirah
Publication year - 2020
Publication title -
journal of pharmacy practice and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.222
H-Index - 22
eISSN - 2055-2335
pISSN - 1445-937X
DOI - 10.1002/jppr.1664
Subject(s) - streptokinase , medicine , checklist , cronbach's alpha , pharmacy , myocardial infarction , pharmacist , medical emergency , family medicine , psychometrics , psychology , clinical psychology , cognitive psychology
Background Although recombinant tissue plasminogen activator has become the first‐line thrombolytic agent, streptokinase remains in use in acute ST‐elevation myocardial infarction (STEMI) patients in Malaysian public hospitals. In a state hospital in Malaysia, all post‐STEMI patients given streptokinase are counselled and issued with a streptokinase card by pharmacists. Due to its highly antigenic nature, knowledge of streptokinase and the streptokinase card serve as an important alert to healthcare providers. This study aimed to develop a validated questionnaire on evaluating knowledge of streptokinase and streptokinase card among post‐STEMI patients. Methods A Malay language questionnaire was developed based on literature review and standard streptokinase counselling checklist. The questionnaire consists of three parts: demographics, knowledge of streptokinase and understanding of streptokinase card. The content of the questionnaire was revised by eight experts (emergency specialists, physicians and pharmacists) and six patients were interviewed via telephone 2 weeks after being issued with a streptokinase card, to test for comprehensibility. Then, a telephone survey was conducted June‐December 2017 involving another 60 patients to test for construct validity and reliability. Results The questionnaire was finalised by decreasing the overall number of items from 6 to 5 (Section B) and 6 to 4 (Section C). The overall measurement of sample adequacy (MSA) was 0.758. Bartlett's test was highly significant (<0.001). The Cronbach's alpha values for Sections B and C were 0.747 and 0.841, respectively. Conclusion Our nine‐item questionnaire is a valid and reliable instrument to assess knowledge of streptokinase and the streptokinase card among Malaysian post‐STEMI patients.