Premium
Enhanced sensitivity of a glutathione‐deficient yeast strain to thiram and dimethyldithiocarbamic acid
Author(s) -
Elskens Marc, T.,
Penninckx Michel, J.
Publication year - 1995
Publication title -
zeitschrift für pflanzenernährung und bodenkunde
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 87
eISSN - 1522-2624
pISSN - 0044-3263
DOI - 10.1002/jpln.19951580116
Subject(s) - glutathione , thiram , strain (injury) , yeast , chemistry , toxicity , biochemistry , metabolism , biology , pesticide , enzyme , organic chemistry , anatomy , agronomy
The sensitivity of a glutathione‐deficient mutant of yeast towards thiram and dimethyl dithiocarbamic acid was compared to that of a wild strain. It was shown that the GSH contents of the cell correlated with the toxicity of both drugs, and that glutathione is probably involved in the metabolism of these drugs.