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Peri‐implant mucositis sites with suppuration have higher microbial risk than sites without suppuration
Author(s) -
Wang Qi,
Lu Hongye,
Zhang Li,
Yan Xia,
Zhu Bin,
Meng Huanxin
Publication year - 2020
Publication title -
journal of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.036
H-Index - 156
eISSN - 1943-3670
pISSN - 0022-3492
DOI - 10.1002/jper.19-0634
Subject(s) - mucositis , fusobacterium , peri implantitis , biology , microbiome , microbiology and biotechnology , fusobacterium nucleatum , implant , dentistry , medicine , periodontitis , bacteroides , bacteria , surgery , bioinformatics , porphyromonas gingivalis , chemotherapy , genetics
Background The aims of the present study were to compare the microbial differences between peri‐implant mucositis sites with or without suppuration, and to construct a classification model with microbiota. Methods Twenty‐four implants with peri‐implant mucositis were divided into suppuration (SUP) group and non‐suppuration (Non‐SUP) group. Clinical assessments of bleeding index, probing depth, suppuration following probing (SUP) were recorded. Submucosal samples were collected from mesiobuccal sites and distobuccal sites, and analyzed by 16S rRNA gene sequencing. Generalized linear mixed model was used to adjust age, gender, location of implants, and intraindividual correlation. Results It was demonstrated that the microbial richness was lower in SUP group. The relative abundance of some pathogenic taxa, such as genera of Fusobacterium , Tannerella , and Peptostreptococcus , were significantly higher in SUP group than Non‐SUP group. In addition, SUP group had less Gram‐positive bacteria, aerobic bacteria, and more metabolic pathway related to life activity. The classification model constructed with 12 genera got a 100% accuracy in identifying sites with or without suppuration. Conclusions The results from this study demonstrate a higher pathogenicity of microbiome at peri‐implant mucositis sites with suppuration than without suppuration, which supports suppuration as a clinical indicator for higher microbial risk.