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Local bone quality affects the outcome of prosthetic total knee arthroplasty
Author(s) -
Huang ChuanChing,
Jiang ChingChuan,
Hsieh ChangHsun,
Tsai ChiaJung,
Chiang Hongsen
Publication year - 2016
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.23003
Subject(s) - medicine , osteoarthritis , bone mineral , osteoporosis , arthroplasty , visual analogue scale , surgery , total knee arthroplasty , alternative medicine , pathology
Osteoporosis and osteoarthritis commonly coexist in the elderly. In patients undergoing prosthetic total knee arthroplasty (TKA), the bone quality around the knee joint may affect the safety of prosthetic implantation and consequently satisfaction with the surgical outcome. We recruited 50 postmenopausal women undergoing TKA for primary osteoarthritis; 43 completed the study protocol. The bone quality parameters of the operated knee, including bone mineral density assessed using dual‐energy X‐ray absorptiometry and microarchitecture variables assessed using micro‐computed tomography, were determined. Surgical outcomes were assessed according to immediate (<1 week) postoperative pain quantified using the visual analog scale and knee function quantified using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 2 and 6 months postoperatively. The influence of bone quality parameters on surgical outcomes was analyzed using simple and multiple regression analyses. Volumetric bone mineral density ( R 2  = 0.187–0.234, p  < 0.01), the structural model index ( R 2  = 0.103–0.181, p  < 0.05), and trabecular separation ( R 2   = 0.289–0.424, p  < 0.05) were significantly associated with postoperative pain and improvement according to the KOOS. In conclusion, local bone quality, including mineral content and microarchitecture, affects the surgical outcome of TKA. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:240–248, 2016.

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