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Noninvasive monitoring of elevated intramuscular pressure in a model compartment syndrome via quantitative fascial motion
Author(s) -
Lynch John E.,
Lynch John K.,
Cole Steven L.,
Carter Jonathan A.,
Hargens Alan R.
Publication year - 2009
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.20778
Subject(s) - medicine , blood pressure , ultrasound , compartment (ship) , nuclear medicine , receiver operating characteristic , ankle , cardiology , surgery , anesthesia , radiology , oceanography , geology
Compartment syndromes, conditions of elevated intramuscular pressure (IMP) resulting from trauma or chronic overuse, frequently require invasive IMP monitoring for accurate diagnosis. Our objective was to test a noninvasive ultrasound technique for estimating IMP based on fascial displacement waveforms from arterial blood pressure pulses. IMP was increased in the legs of 23 healthy adult subjects up to 80 mmHg using two blood pressure cuffs covering the region from the knee to the ankle. Receiver operator characteristic curves and recursive partitioning were used to determine the sensitivity and specificity of diagnosing elevated IMP using fascial displacement. For one curve, in which several ultrasonic measurement parameters were used along with subject body mass index and blood pressure, the sensitivity and specificity for diagnosing normal IMP (below 30 mmHg) from elevated IMP (30 mmHg and up) was 0.61 and 0.94, respectively. Recursive partitioning, in which IMP was divided into three ranges (normal <30 mmHg, midrange of 30–40 mmHg, and elevated ≥50 mmHg), resulted in improved diagnostic sensitivity (0.77) with almost no change in specificity (0.93). © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 27: 489–494, 2009